1. Demetrious Johnson vs. Henry Cejudo 2
Demetrious Johnson and Henry Cejudo first faced off at UFC 197 for the flyweight title and Johnson finished Cejudo in the first round. Two years later Cejudo would get another shot at "Mighty Mouse" who was coming off 13 straight wins and 11 straight title defenses, a UFC record. Johnson and Cejudo would serve as the co-main event for TJ Dillashaw and Cody Garbrandt at UFC 227.
Johnson dominated the first round after Cejudo had trouble with his left leg, though Cejudo did pour it on at the end of the round. Cejudo picked up the pace in the second round, landing a significant takedown but losing the striking battle. Johnson took control in the third, doubling up Cejudo in strikes while drawing blood and landing the lone takedown.
Cejudo won the fourth round, out-landing Johnson and finishing the round in the top position. The fifth round was close, with Cejudo edging out the total strikes and landing another takedown. Though Johnson landed 30 more significant strikes than Cejudo, Cejudo won the grappling exchanges, and the fight was declared a split decision win for Cejudo by the slimmest of margins, making him the one to unseat the flyweight king.
This fight was important because Johnson was eventually traded to ONE Championship where he added another title to his mantle and is scheduled to defend it in May. Cejudo would defend the flyweight title and then move up to claim the bantamweight championship, becoming the fourth fighter to hold titles in two different weight classes simultaneously. Cejudo would retire in 2020 but come out of retirement in 2023 and will face current bantamweight champion Aljamain Sterling at UFC 288.